The chemistry of biomolecules is the essence of biochemistry: a study of the structure, function and role of biology in proteins, nucleic acids, carbohydrates and lipids. The biochemistry curriculum at Hillsdale College seeks to provide students with a strong background in chemistry and the cellular/molecular branch of biology. This foundation provides the knowledge to understand the important advances that have occurred at the interface of chemistry and biology. The Chemistry Department offers a major or minor in biochemistry.

The biochemistry major at Hillsdale is designed to prepare students for careers in biochemical and biotechnical research, graduate study in biochemistry, and for further education in professional schools in medicine, dentistry and allied health fields. The courses for the major draw from both the Chemistry and Biology Departments. The required courses follow the recommendations of the American Society of Biochemistry and Molecular Biology.